The St. Louis Cardinals, in conjunction with Major League Baseball’s league-wide release, yesterday announced their 2022 regular season schedule. The Home Opener is scheduled for Thursday, April 7, against Pittsburgh as part of a six-game homestand featuring four games with the Pirates (April 7, 9-11) and two games versus the cross-state rival Kansas City Royals (April 12-13).
The Cardinals will open the 2022 season on the road with a three-game series at Pittsburgh beginning on Thursday, March 31, followed by a two-game series at Wrigley Field against the Chicago Cubs on April 4 and 6.
The Cardinals 20-game Interleague schedule features matchups with all five AL East opponents for the first time since the 2017 season. Highlighting those matchups are a three-game weekend series versus the New York Yankees at Busch Stadium on August 5-7 (their first series at Busch Stadium since 2014).